Two sample MR report
CBWD1_Alveolar Macrophages against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 11 | -0.1459358 | 0.0947242 | 0.1577923 |
| Weighted median | 11 | -0.0825632 | 0.0142434 | 0.0000000 |
| Inverse variance weighted | 11 | -0.0780234 | 0.0110441 | 0.0000000 |
| Simple mode | 11 | -0.0852181 | 0.0220456 | 0.0031318 |
| Weighted mode | 11 | -0.0847333 | 0.0209653 | 0.0023552 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.102371 | 9 | 0.9991631 |
| Inverse variance weighted | 1.623471 | 10 | 0.9984966 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0601985 | 0.0833921 | 0.4887021 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005565 | 1e-07 | TRUE | 0.0258872 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
